SkinMedica TNS Line Refine is a targeted formula for filling in fine lines and wrinkles around the mouth and eyes. It is designed to precisely and effectively diminish the appearance of fine lines and wrinkles around the eyes and mouth. In a matter of seconds, SkinMedica TNS Line Refine smoothes, tightens and fills in fine lines for a more youthful complexion. The anti-wrinkle treatment also provides long term anti-aging benefits by delivering peptides and growth factors to promote cell activity and maintain healthy skin. SkinMedica TNS Line Refine Benefits:Diminishes fine linesPlumps skin with hyaluronic acidCreates an even texture SkinMedica TNS Line Refine Directions:Apply twice daily, AM and PM, or as needed. Remove cap and slowly twist top end of the applicator in a clockwise direction to release TNS Line Refine into the applicator. The product will become visible on one side of the applicator only. After applying a moisturizer gently pat the product onto the line with your finger tips.